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Description

In the SURMOUNT-1 trial, 24-26% of participants experienced nausea at some point during the study, most commonly during dose escalation phases

Taking vitamin B 12 supplements affects the genes expressed by bacteria living on our skin, report researchers at the University of California, Los Angeles (UCLA) in Science Translational Medicine [1] on 24 June 2015

These are generally worst during dose escalation (weeks 4-10) and improve thereafter

Before starting B12 supplements , particularly high-dose formulations, discuss with your GP if you have: A history of sleep disorders Existing anxiety or mood disorders Cardiovascular conditions Kidney disease (which may affect B12 metabolism and test interpretation) Leber's hereditary optic neuropathy (cyanocobalamin is contraindicated