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Simon E, et al

However, not only does p62 prevent NRF2 binding to KEAP1, it induces autophagic degradation of KEAP1, resulting in a positive feedback loop of NRF2 activation [82]

10.5551/jat.RV17057 46

Secondary analysis compared outcomes among different prior therapy when VAD regimen was obligatory as first line induction regimen for transplant eligible patients and bortezomib based therapy could be used only in patients with renal failure or cardiac co-morbidity in our country