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routes of administration include, but are not limited to, oral, buccal, inhalation, intradermal, subcutaneous, transmucosal, transdermal, or topical administration

Still, they did not find expression changes in Foxp3 + T cells, immunomodulatory cytokines IL-10 or IL-33, and TJ protein zonula occludens 1 (106)

Abbreviations AUC: Area under the curve DNR: Do not resuscitate Gln: Glutamine ICU: Intensive care unit ROC: Receiver operating characteristic ROSC: Return of spontaneous circulation SAPS: Simplified Acute Physiology Score SOFA: Sequential Organ Failure Assessment References Tjder I, Rooyackers O, Forsberg AM, Vesali RF, Garlick PJ, Wernerman J

Consequently, increased local bioavailability of phytochemicals in the gut allows them to directly modulate the function and phenotype of intestinal DCs, potentially shaping mucosal immune responses more effectively