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First, sufficient iron is necessary to maintain testosterone synthesis and spermatogenesis [5], and second, excess iron affects sperm quality by inducing oxidative stress and lipid peroxidation, thus leading to male reproductive dysfunction [6, 7]

This remarkable 15-amino acid sequence (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) has demonstrated extraordinary healing and protective properties across multiple tissue types and organ systems in extensive preclinical research

NNMT is expressed in multiple tissues but is particularly abundant in adipose and hepatic cells, where it participates in nicotinamide utilization and impacts NAD-related pathways

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