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Because it acts rapidly, Albuterol is the first-line rescue medication for shortness of breath and bronchospasm

DCI arises not only from large-vessel vasospasm, but also from other complex pathophysiological processes, including thrombo-inflammation, neuro-inflammation, microcirculatory dysfunction, and glycocalyx disruption

Novel strategies under investigation include biomarker-guided therapy using circulating nitric oxide metabolites or endothelin-1 levels, and genetic profiling to identify responders to specific antihypertensive agents 48

These results suggested that the upregulation of GPX1 promotes, while the deficiency of GPX1 suppresses, the survival of SGNs after peroxynitrite injury