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[352] It plays a role in regulating intraocular pressure in the eye through its potential complex interaction with nitric oxide, a crucial signaling molecule affecting blood vessel dilation

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Finally, phosphorylation of S377 on AMPK2 associated with glucose uptake in insulin-stimulated and/or exercised skeletal muscle from individuals with differing muscle insulin sensitivity, and was necessary for proliferation of MEF cells during glucose deprivation, suggesting a regulatory role in glucose metabolism [35]