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Photoswitchable click amino acids: light control of conformation and bioactivity

Seddon AR, Liau Y, Pace PE, Miller AL, Das AB, Kennedy MA, Stevens AJ Genome-wide impact of hydrogen peroxide on maintenance DNA methylation in replicating cells

Dysbiosis disrupts the intestinal epithelial barrier, facilitating the translocation of bacterial productssuch as LPSinto the bloodstream and triggering systemic inflammation, a process referred to as endotoxemia

The HPGDS inhibitor TAS205 has been developed for DMD treatment 22,23 based on the demonstrated role of PGD 2 , which is produced by HPGDS, in muscle fiber necrosis underlying DMD 10,19,20,21