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Enzyme distribution along the nephron

Overall, the studies performed in vitro and in vivo using high-dose VitC as single agent in a large number of cancer types, have shown that it is a promising anti-cancer agent impairing both tumor growth and metastasis

This process was supported by scRNA-seq analysis and lineage tracing studies using a mouse model of endometrial repair, which identified platelet-derived growth factor alpha (PDGFRa) as a marker for the stromal cells involved [15]