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Even if patients with AKI survive the acute stage, AKI can develop to CKD and progress to end-stage renal disease, which causes a huge social burden (Chen et al., 2018

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263 Fluorescence correlation spectroscopy, which uses confocal microscopy to observe fluorescently labeled molecules that transit through an observation volume to measure the oligomeric state of the protein(s) (Figure 9), 70,562 can evaluate the interactions and oligomeric state of the expressed proteins or complexes directly in a CFE reaction

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