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However, it is also possible that a basic tone of glucagon stimulation is required to maintain normal somatostatin secretion, without which responses to other stimuli are lost

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10.1016/j.neuron.2012.01.034 463 OsterweilE

This review will explore the recent developments in the tumour-targeting properties of a specific group of NIRF cyanine dyes and the preclinical evidence for their potential as drug-delivery systems in the treatment of primary and metastatic brain tumors