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As the N-terminal protein sequence of SMT15 extended to 46 amino acids, the SMT15 N46 :eYFP protein was found to target to the chloroplast (Figure 2B), indicating that the first 46 aa of SMT15 is sufficient to guide the protein into the chloroplast

Our findings also suggested the induction of necroptosis during ferroptosis in erastin-treated acute monocytic leukemia THP-1 cell lines after treatment with an inhibitor of N-myristoyltransferase IMP-366

Individuals with gastrointestinal issues: People living with disorders of the stomach or small intestine may have a more difficult time absorbing vitamin B12 from their food

The hGAN-G332R mice showed complete gigaxonin loss compared to hGAN and wild-type C57BL/6 control mice, similar to GAN patient neurons with the G332R mutation