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Williams, University of Toledo, United States

Oxidative stress arises from an imbalance between reactive oxygen species (ROS) and cellular antioxidant defenses, contributing to DNA damage, protein misfolding, and cellular aging

TRPV1 activation alleviates cognitive and synaptic plasticity impairments through inhibiting AMPAR endocytosis in APP23/PS45 mouse model of Alzheimer's disease

Heat therapy through modalities such as a sauna or even local heating (as is the case in this study) may ultimately serve as a very useful alternative or adjunct therapy to maintain skeletal muscle metabolic function and preserve muscle mass