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Tumor-derived myeloid-derived suppressor cells (MDSCs) are critical tumor immunosuppression components

7-Monohydroxy-ethylrutoside seems to provide similar cardiotoxicity protection as dexrazoxane in mice (Jacobs et al., 2011)

Herein, we have approached this by analyzing transcriptomic and metabolomic responses elicited in colon cancer cells that persist after exposure either to the CDK4/6i Palbociclib or the glutaminase inhibitor Telaglenastat (CB-839), or their combination, in vitro and in vivo