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Ultrapure water (18.2 Mcm) was provided by a Milli-Q filtration instrument

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They contain unusually high levels of the master antioxidant glutathione This powerful antioxidant can reactivate other antioxidants and is important for the detoxification of heavy metals as well as other contaminants

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FFA-mediated endothelial dysfunction involves several mechanisms, including dysregulated production of nitric oxide and cytokines, metaflammation, oxidative stress, inflammation, activation of the renin-angiotensin system, and apoptosis

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Daily glutathione use is common in clinical practice, though some providers recommend cycling (e.g., 5 days on, 2 days off) to prevent adaptation

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