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As a standalone, the weight loss is more modest than GLP-1 agonists, with trial data showing around 10 to 11% body weight loss at 2.4 mg over 32 weeks

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10.1007/s00425-009-1075-3 155 YoonH

This comprehensive review critically examines recent advances in targeting ferroptosis, an iron-dependent form of non-apoptotic cell death mediated through reactive oxygen species (ROS) accumulation and lipid membrane peroxidation, for therapeutic intervention in GBM