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(Studies have shown that everyone with an autoimmune disorder, including Hashimotos, has some degree of intestinal permeability

for example, IL-1 can damage endothelial tight junctions, inhibit astrocytic production of Sonic Hedgehog (SHH) signaling, and induce the release of further pro-inflammatory factors, thereby exacerbating neuroinflammation (Bronisz et al., 2023)

Cholesterol can be synthesized endogenously and is present in all the body's cells, where it participates in many physiological functions, including fat metabolism, hormone production, vitamin D synthesis, and cell membrane integrity

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