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In gastric cancer, the upregulation of WTAP, a subunit of the METTL3 complex, boosts TGF- expression

Dietary recommendations for fatty liver disease include: Reducing intake of refined carbohydrates and added sugars, particularly fructose-containing beverages Limiting saturated fats whilst incorporating healthy fats from sources like olive oil, nuts, and oily fish Increasing consumption of fruits, vegetables, and whole grains Following a Mediterranean-style diet, which has shown particular benefit in NAFLD Limiting alcohol consumption in line with UK Chief Medical Officers' guidance (maximum 14 units per week spread over at least three days, with several alcohol-free days), or abstaining completely if advised by your clinician Physical activity provides benefits independent of weight loss

However, leptin concentration exhibited a significant increase ( p = 0.005) in the obese patients in contrast to the control group

the American Cancer Society (PF20-105-01-DMC to S.D.W.)