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In the later stages of reperfusion, the CD62L+ subpopulation releases non-lethal NETs via mtDNA, whose unmethylated CpG motifs activate the TLR9/STAT3 pathway in HSCs, promoting collagen deposition and angiogenesis

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286 Compared with those in the control group, the hepatic CTGF levels and severity of liver fibrosis were lower in the hepatocyte-specific p53-deficient group, whereas the extent of hepatocyte apoptosis was similar