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Retrieved December 17, 2020

Mol Cell Biol 21: 12491259 Marciniak SJ, Yun CY, Oyadomari S, Novoa I, Zhang Y, Jungreis R, Nagata K, Harding HP, Ron D (2004) CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

This review delineates the molecular and cellular pathways by which Hg exerts neurotoxic effects, emphasizing its disruption of the glutamateglutamineGABA cycle and the resulting excitotoxic activation of NMDA receptors