glutathione for leukemia overproduction mediates lymphoma initiating cells survival and has a sex-dependent effect on lymphomagenesis Excited to share our #RedoxBiology
Excited to share our #RedoxBiology @sciencedirect @SFRBM article showing that #epigenetic defect in #leukemia creates vulnerability for #ferroptosis upon the use of #glutathione inhibitors, work led by Lucas Pontel @LucPontel @CarrerasIJC https: t.co Glutathione determines chronic myeloid leukemia vulnerability to an inhibitor of CMPK and TMPK Communications Biology Human cancer associated fibroblasts enhance glutathione levels and antagonize drug induced prostate cancer cell death Cell Death & Disease Dysregulated glutathione metabolism impairs natural killer cell function in patients with acute leukemia ScienceDirect
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