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Blood sample Fasting blood samples were freshly withdrawn from all subjects under investigation on heparin after an overnight fasting inpatient King Fahd hospital

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These effects reflect the vast and diverse biological mechanisms through which diet interacts with human physiology ( 3.1 Cardiometabolic health Plant-based diets can impact cardiometabolic health through various means such as effects on lipid profiles, systemic inflammation reduction, insulin sensitization, and effects on body weight ( Plant-based diets have been consistently associated with lower body mass index, which considered as one of the major drivers of cardiometabolic risk and additionally with lower incidence of obesity

Left panel : Low-dose IV ACh primarily activates endothelial M3 muscarinic receptors, stimulating nitric oxide (NO) release and vascular smooth muscle relaxation, resulting in arterial vasodilation and reduced blood pressure