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van der Venne, Health and Safety Directorate, Commission of the European Communities, Luxembourg PREFACE At a joint meeting of the World Federation of Associations of Clinical Toxicology and Poison Control Centres, the International Programme on Chemical Safety (IPCS), and the Commission of the European Communities (CEC), held at the headquarters of the World Health Organization in October 1985, the evaluation of antidotes used in the treatment of poisonings was identified as a priority area for international collaboration

GLUTATHIONE An amino acid that contributes to immune defense because it is required by the immune system for two important reasons: it protects host immune cells through its antioxidant mechanism and it provides the optimal functioning of lymphocytes and other cells of the immune system

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The retrospective, single-arm design without a control group limits causal inference, as placebo effects, regression to the mean, natural symptom fluctuation, and the standardized rehabilitation protocol may have contributed to observed improvements