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Abstract All organisms have thioredoxin reductase (TR) or glutathione reductase (GR), the only enzymes that use reduced nicotinamide adenine dinucleotide phosphate to reduce cytosolic disulfides into thiols, thereby powering deoxyribonucleotide biosynthesis, elimination of oxidants, oxidative damage repair and reduction of the disulfide nutrient cystine into the thiol amino acid cysteine

Known as the master antioxidant, Glutathione is essential for detoxifying the body, improving cellular health, and promoting a luminous, youthful look all from the inside out

Further research may focus on the direct loading of bioactive peptides or proteins into extracellular vesicles for tissue repair

135 Therefore, the unique metabolic vulnerabilities of cancer cells, which differ from those of normal cells, can be strategically targeted to develop novel and effective therapeutic interventions