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The C-APC policy payment methodology set forth in the CY 2014 OPPS/ASC final rule with comment period and modified and implemented beginning in CY 2015 is summarized as follows (78 FR 74887 and 79 FR 66800): Basic Methodology

13 AlphaFold has combined numerous deep learning innovations to predict the three-dimensional (3D) structures of proteins at or near experimental scale resolution, inspiring the community (including us) to rethink studies of function, evolution, and disease (e.g., refs (413))

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