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Nature, 543 (7608), 494-499

An examination using murine models of coronary artery tying appeared to exhibit results which implied that TB-500 might elevate integrin-associated kinase (ILK) and protein kinase B operations in the heart, possibly boosting early cardiomyocyte endurance and seemingly enhancing heart performance

FSP1 is a redox enzyme that operates through its NAD(P)H-binding domain and FAD-binding domain, enabling it to exist in reduced forms, specifically CoQH2 and VKH2, from CoQ and vitamin K (VK), respectively