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5.3 Acute lung injury Due to the presence of extensive capillary beds in the lungs and the abundance of immune cells in the lung parenchyma, the systemic inflammatory response activated by ECMO renders lung tissue extremely susceptible to acute injury (114, 115)

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NADPH oxidases facilitate the transfer of electrons from NADPH to molecular oxygen, leading to the generation of the free radical superoxide and various downstream reactive oxygen species (ROS)

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into H 2 O 2 and O 2 , and is key in the regulation of OS, cell damage (Mattiazzi et al., 2002

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antigens with improved expression, folding, stability and purification profile under a variety of chromatographic conditions can be very important improvements to incorporate for the vaccine manufacturing process

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