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The most sought-after traits by blueberry breeders are larger size, better flavour, increased bloom (coating of wax), easy detachment of fruit for harvesting by hand or machine, minimum scarring where fruit detaches from the pedicel, firmness, and long shelf life [14,19]

Additionally, rats given TNBS experienced severe bloody diarrhea, an increased colon weight-to-length ratio, a macroscopic damage score, goblet cell loss, submucosal edema, increased inflammatory cell infiltration, and a marked weight loss (259)

FXR Intestinal FXR activation can increase the production of ceramide in the ileum, which transfers into the liver and subsequently activates SREBP-1c to increase fatty acid production, resulting in hepatic steatosis [185]