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Description

Hernandez-Olivan P

Ultimately, personalized nutritional strategies-incorporating genetic background, trace element status, and gut microbiota composition-represent a promising direction for the precise prevention and management of AITD ( Figure 1 )

Author contributions SAC: Writing review & editing, Conceptualization, Validation, Writing original draft, Supervision, Data curation

The gastric cancer tumor microenvironment is shaped by coordinated immune evasion, where tumor cells recruit suppressive populations (TAMs, MDSCs, and Tregs) and dampen effector T-cell and NK-cell function through checkpoint signaling, soluble mediators, and metabolic inhibitory circuits such as adenosine (155159) ( Supplementary Table 1 )