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RSL3 suppresses spheroid formation and viability, and halts migration of PTC cells in vitro We postulated that the RSL3-mediated suppression of thyroid tumor cell viability is a ferroptosis pathway-dependent process, therefore, we treated K1 cells with a lethal dose of RSL3 alone and in the presence of either a ferroptosis inhibitor Fer1, or a pan caspase inhibitor, Z-VAD-FMK (ZVAD) and measured cell viability

The study investigated the best concentration of DTNB by examining a range of concentrations from 100 to 5 mM, including 100, 500, 1, 2, 3, 4, and 5 mM

10.1016/j.ebiom.2023.104744 Summary Keywords diabetic cardiomyopathy, NADPH oxidase, reactive oxygen species, oxidative stress, redox signaling pathways Citation Ye Z, Wang S, Wan Z, Huang B and Guo J (2025) Targeting NADPH oxidase-driven oxidative stress in diabetic cardiomyopathy: mechanisms and therapeutic perspectives

Antioxidant therapy and bipolar disorder Coenzyme Q10 (ubiquinone, see also above) is a substance produced naturally by the body and has been found to be effective in alleviating symptoms of bipolar disorder