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Handling and Storage Recommendations To preserve sample integrity and support safe laboratory practices, the following guidelines should be followed: Store at 20 C or below (non-frost-free preferred)

Over 24 hours, lactose is fermented, beneficial microbes multiply, and the liquid transforms into a lightly carbonated, probiotic-rich beverage

Araj et al 2025)

Indeed, while it was reported a beneficial effect of vitamin B 12 (cyanocobalamin) in reducing homocysteine levels and thus cardiovascular risk, recently it has been suggested that an excess of vitamin B 12 might have harmful cerebrovascular consequences (Duschek et al., 2016)