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Peptides derived from cytoskeletal proteins also tended to increase in abundance with age, including proteoforms of dematin actin-binding protein (DMTN), paralemmin-1 (PALM) and microtubule-associated proteins 1/2 (MAP1/2), which may represent degradation of full-length cytoskeletal proteins in later life, leading to cytoskeletal instability 36

Injection Site Reactions: Redness, swelling, or mild pain at the injection site are possible and typically resolve quickly with proper injection techniques

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Research-grade versus pharmaceutical-grade Research-grade lyophilized tirzepatide is manufactured and sold for laboratory research purposes