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The identification of specific, mutation-dependent metabolic vulnerabilities in particular cancers by targeting them to synergize with radiotherapy, chemotherapy, or immunotherapy to induce cytotoxicity is suggested

[DOI] [PMC free article] [PubMed] [Google Scholar] 206.Pavlov PF

reported elevated expression levels of glycolysis-related enzymes such as lactate dehydrogenase A (LDHA), PKM2, and monocarboxylate transporter 4 (MCT4) in associated fibroblasts, further supporting the reverse Warburg effect

While not FDA-approved, green tea extract is commonly used to help decrease inflammation and reduce blood pressure