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Thymoquinone-encapsulated chitosan nanoparticles coated with polysorbate 80 as a novel treatment agent in a reserpine-induced depression animal model

Informed consent was obtained from all participants in the study and the study was approved by the Scientific Ethical Committee of Rennes Hospital in France (Avis n 22.185)

In addition, reactive metabolites-proteins adducts are thought to be a principal factor in natural drug-induced liver injury

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