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Ideally, this framework is further enriched with metagenomic analysis of the gut microbiome, which provides valuable insights for functional decision-making (Proctor et al., 2019), and with a pharmacogenomic profile, particularly in cases requiring pharmacotherapy or where patients are already on complex polypharmacy regimens

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After the patient had experienced multiple acute reactions, suspicion was directed to red-colored foods, especially those consumed at restaurants, as possible triggers