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Notably, several aging-related signaling pathways are interconnected with the molecular clockwork

Glutathione pulls its weight in this process, working within the liver to neutralize harmful substances and support their elimination from the body through the bile

10.1016/s0021-9258(19)50300-3 119 LiY.MoucheS.SajicT.Veyrat-DurebexC.SupaleR.PierrozD.et al (2012)

This finding further highlights the crucial role of ferrous iron overload in alcohol-induced ferroptosis, as H 2 O 2 generated by POR initiates a Fenton reaction with labile iron to produce hydroxyl radicals, leading to lipid peroxidation [27]