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That matters because both estrogen deficiency and polycystic ovary syndrome (PCOS) can make it easier to store fat in the liver

San Koh C, Didierjean C, Navrot N, Panjikar S, Mulliert G, Rouhier N, Jacquot JN, Aubry A, Shawkataly O, Corbier C (2007) Crystal structures of a poplar thioredoxin peroxidase that exhibits the structure of glutathione peroxidases: insights into redox-driven conformational changes