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When toxic burden is high, toxins recirculate, detox pathways get overwhelmed, and inflammation keeps the system from moving forward

This is mechanistically different from GLP-1 receptor agonists like semaglutide or tirzepatide, which are large peptide chains stabilised by complex tertiary structures that degrade slowly even at suboptimal temperatures

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It also exibits questionable behaviour in the presence of UV light and was the center of a debate between the non-profit group, EWG (whose intentions are no doubt good, but its credibility is often questioned by scientists) and a group of scientists and dermatologists lead by Steven Q