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Potential of these effects may be heightened in patients with breast cancer treated with hepatically metabolized chemotherapeutics (e.g., cyclophosphamide, paclitaxel, anthracyclines) or tyrosine kinase inhibitors in which drug-drug interaction-based elevation or lowering of enzyme activity can result in supra-therapeutic drug concentrations, accumulation of toxic metabolites and compromised detoxification of reactive oxygen species facilitating hepatocellular distress

One could imagine it working as well, or even better, for younger children, because their brains are still developing

This drug was found safe and effective in five patients with dermatomyositis to the point that prednisone was reduced or discontinued (120)