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Constitutive activation of c-Met is correlated with c-Met overexpression and dependent on cellmatrix adhesion in lung adenocarcinoma cell lines

However, the protective effect of internalization is limited, since treatments of 7 days or longer will all eventually induce analgesic tolerance [37, 78, 81, 82] independent of the degree of internalization triggered by the agonist

As expected, stimulation of hippocampal neurons transfected with mRFP--actin with HGF, Dihexa and Nle1-AngIV had significantly enhanced dendritic arbors while those additionally transfected with she-Met RNA were no different from control treated neurons (FIG

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