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The interactions of other foods (such as high-protein and alkaline foods) lack direct data and are not yet listed as major restrictions (Nkhili et al., 2014)

Regulatory and quality concerns : Enema equipment may fall under MHRA medical device regulations, but coffee solutions are not licensed medicines

Inhibition of hypoxia-inducible factor-1alpha (HIF-1alpha) protein synthesis by DNA damage inducing agents

reported that the KDM5A inhibitor ZINC33576 can effectively inhibit the demethylation activity of KDM5A, block the cell in G1 phase, and induce cell senescence, thereby playing an anti-proliferative effect (Table 4)