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Dysbiosis, triggered by chronic stress, alters lipid metabolismparticularly glycerophospholipids like diacylglyceroland provides a molecular framework for understanding the metabolic disturbances in depression

[53] [54] This is because it requires significant damage to the liver to impair bilirubin excretion, hence minor impairment (in the absence of biliary obstruction or Gilbert syndrome) would not lead to jaundice

BJP-IVb prevents PD by inhibiting iron regulatory protein (IRP2) from iron overload-mediated ferroptosis in dopaminergic neurons, as demonstrated by diminished lipid peroxidation and reduced iron content

2000 Dec;130(12):1175-6