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Food Chemistry , 158 , 262269

Therefore, research on the FMT approach to CVD therapy and prevention is still needed

Preclinical studies show that combining decitabine with histone deacetylase inhibitors (e.g., sodium butyrate) synergistically upregulates NIS mRNA expression (by up to 1600-fold) and significantly increases iodine uptake (9-fold in DRO cells, 8-fold in 2-7 cells) [95], supporting epigenetic combination therapy as a viable strategy to overcome resistance