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Similarly, pathway analysis classified genes differentially regulated by EGCG as being involved in sterol metabolic processes, lipid metabolic processes, regulation of the MAPK cascade, and CX3C chemokine receptor binding

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Furthermore, the study demonstrated that the addition of growth hormone to BPC 157-treated fibroblasts activated Janus kinase 2 (JAK2), a key downstream signaling molecule in the GH receptor pathway

These results showed that their combination with existing antibiotics like amikacin may offer potential, but clinical trials are essential to validate their efficacy and safety in TB patients