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The accretion of metabolites frequently arises in plants under stress from numerous elicitors or signaling molecules, as it is recognized that growth conditions like temperature, nutrient supply and lightning conditions influence the accumulation of different natural products (Rini Vijayan and Raghu, 2020)

However, the broader challenge of modernizing TCM research also applies to SCF

By reshaping key signaling axes (e.g., PI3K/AKT and Wnt/-catenin) and rewiring metabolic and microRNA networks, it imposes broad restraint on tumor progression