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The non-genomic mechanism involves the interaction of the ER located in the plasma membrane or its vicinity with adapter proteins, including Shc and Src, as well as signaling through GPR30, resulting in activation of the MAPK cascades, PI3K, and adenylate cyclase (209)

The role of catalases in the prevention/promotion of oxidative stress

However, in stage 2, copper supplementation increased RBD concentration, eventually reaching up to 93 mg/mL, even when cell growth stabilized

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