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Due to the substrate specificity of different esterases, the enzymatic consideration should be systematically incorporated into the early design stage

UCLA Health

Prog Lipid Res 58:113 Bhalani DV, Nutan B, Kumar A, Chandel AKS (2022) Bioavailability enhancement techniques for poorly aqueous soluble drugs and therapeutics

The highest thiolate oxidizability of GSH (383 mV) belongs to the microspecies in which all other basic sites in the molecule are in non-protonated form