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MMP-9-deficient mice display higher production of MUC2 at the mRNA and protein levels, which correlates with increased differentiation of intestinal cells towards the secretory lineages

[5] [6] This effect appears to be dose-dependent and duration-dependent, meaning higher doses and longer treatment periods increase the risk of deficiency

Zhang W, Mehta A, Tong Z, Esser L, Voelcker NH

Women often experience hormonal acne during: Puberty Menstrual cycles Pregnancy Perimenopause and menopause Conditions like PCOS (Polycystic Ovary Syndrome) Unlike general acne, hormonal acne is more likely to be deep, cystic, and inflamed, often leaving marks or scars if untreated