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Doses up to 60mg/kg per day produced no observable toxicity

There was also an improvement in the levels of low-density lipoprotein cholesterol, very low-density lipoprotein cholesterol, and triglycerides in participants who received retatrutide compared to placebo, which did not show improvement

[13] This research primarily focused on the peptide's potential impact on dermal procollagen synthesis, the proliferation and differentiation of keratinocytes (the predominant cell type in the epidermis), and cutaneous inflammation

Administration of BPC-157 at a dose of 10 g/kg or 10 g/kg after lidocaine administration reduced the bradycardia effect within minutes