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48 In another randomized placebo-controlled trial with 170 participants, a combination that included black cohosh, chaste tree, soy, burdock ( Arctium lappa ), and wild yam ( Dioscorea villosa ), taken at a dose of 550 mg twice daily for eight weeks, reduced the frequency and intensity of menopausal night sweats (but not hot flashes)

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Neuropathic pain should be treated with anticonvulsants and/or antidepressants as indicated in the guidelines for the treatment of neuropathic pain, with preference given to gabapentin 3001800 mg (rarely up to 3600 mg), especially in case of concomitant restless legs syndrome, and/or duloxetine 60120 mg, in case of concomitant depression