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Any significant discoloration, particulate matter, or opacity in FDA-approved tirzepatide indicates potential degradation or contamination and the product should not be used

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Patients at risk of or diagnosed with B12 deficiency, including those with anemia, neurological symptoms, or absorption issues, benefit from this injectable therapy

Therefore, it may be more plausible and effective to select stimulation acupoint or stimulation parameters depending on pathophysiology mechanisms of different gastrointestinal diseases, rather than aiming at alleviating symptoms